Chronic extrahepatic portal vein obstruction (CEPVO) in the absence of cirrhosis refers to a portal vein thrombosis present or persistent for more than 6 months or to a portal cavernoma.
Main complications of CEPVO are related to portal hypertension, and probability of having high-risk varices (i.e. large varices, or small varices with red spot signs, or variceal hemorrhage revealing portal cavernoma) is about 55% at baseline endoscopy (1). Plus, probability of developing high-risk varices during follow-up is about 25%.