Reply To: Advice on a clinical case, LTX for extreme splenomegaly

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#2373

Dear colleague,
Thank you for sharing with us this case.
1. Has a myeloproliferative neoplasm been firmly ruled out? With such a large spleen, it is important.
2. I would be reluctant to splenectomy or to any procedure like splenic artery embolization.
3. I agree with Dr Daniel R. Ganger than portal vein recalization should be considered.
4. Liver transplantation is indeed the option if portal vein recanalization is not feasible/fails and if there is a patent superior mesenteric vein.
Best regards
Pierre-Emmanuel Rautou

Hôpital Beaujon, Clichy, France